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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WWOX
All Species:
3.72
Human Site:
S411
Identified Species:
6.29
UniProt:
Q9NZC7
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZC7
NP_057457.1
414
46677
S411
L
I
Q
E
R
L
G
S
Q
S
G
_
_
_
_
Chimpanzee
Pan troglodytes
XP_001144696
363
41022
Rhesus Macaque
Macaca mulatta
XP_001105944
398
45056
Dog
Lupus familis
XP_852623
383
43043
Cat
Felis silvestris
Mouse
Mus musculus
Q91WL8
414
46494
S411
L
I
Q
D
R
L
G
S
P
S
S
_
_
_
_
Rat
Rattus norvegicus
NP_001099658
356
40173
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505354
146
16628
F143
G
F
K
S
G
E
T
F
A
E
I
_
_
_
_
Chicken
Gallus gallus
Q5F389
414
46711
R411
L
I
R
E
Q
L
G
R
R
S
P
_
_
_
_
Frog
Xenopus laevis
NP_001088080
143
16305
Zebra Danio
Brachydanio rerio
Q803A8
412
46303
P408
L
V
Q
E
R
S
T
P
P
Q
V
L
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLU5
409
46492
Q406
L
I
A
E
L
V
E
Q
E
Q
H
_
_
_
_
Honey Bee
Apis mellifera
XP_395282
414
46992
K404
M
I
I
N
I
M
K
K
D
K
L
W
E
T
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789399
410
45991
K407
I
I
K
E
A
L
S
K
N
S
L
_
_
_
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42536
405
43844
E399
R
R
V
W
E
V
S
E
K
L
V
G
L
A
_
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.5
84.7
82.8
N.A.
93.7
81.1
N.A.
26
83
29.2
71.9
N.A.
48.3
51.2
N.A.
56.2
Protein Similarity:
100
86.2
88.4
87.4
N.A.
96.1
83.8
N.A.
29.4
93
33.3
84.3
N.A.
65.2
66.6
N.A.
73.4
P-Site Identity:
100
0
0
0
N.A.
72.7
0
N.A.
0
54.5
0
33.3
N.A.
27.2
6.6
N.A.
36.3
P-Site Similarity:
100
0
0
0
N.A.
81.8
0
N.A.
9
81.8
0
41.6
N.A.
45.4
20
N.A.
54.5
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
21.4
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
0
0
8
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
36
8
8
8
8
8
8
0
0
8
0
0
% E
% Phe:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
8
0
22
0
0
0
8
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
8
43
8
0
8
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
0
15
0
0
0
8
15
8
8
0
0
0
0
0
% K
% Leu:
36
0
0
0
8
29
0
0
0
8
15
8
8
0
8
% L
% Met:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
15
0
8
0
0
0
0
% P
% Gln:
0
0
22
0
8
0
0
8
8
15
0
0
0
0
0
% Q
% Arg:
8
8
8
0
22
0
0
8
8
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
0
8
15
15
0
29
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
15
0
0
0
0
0
0
8
0
% T
% Val:
0
8
8
0
0
15
0
0
0
0
15
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
43
50
50
58
% _